The last but not least, is three column navigation. The typical three column layout has a wide center surrounded by  left and right narrow columns. Three column layouts can easily appear cluttered – so white space is essential! Three column layouts are used for sites that have tons of navigation, short bits of content (such as quotes) and advertising.

The apple store is an example of  3 column layout, fortunately it only has 3 columns on the home page and there is plenty of white space to keep your eye moving.